Najam A Sharif Selected Research

1-(2-aminopropyl)-1H-indazole-6-ol

8/2010	Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action.
2/2007	AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist.

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Najam A Sharif Research Topics

Disease

11	Ocular Hypertension (Glaucoma, Suspect) 01/2023 - 07/2003
9	Glaucoma 01/2023 - 01/2006
4	Hyperemia 01/2009 - 09/2004
3	Stroke (Strokes) 01/2023 - 05/2016
3	Hypersensitivity (Allergy) 01/2023 - 12/2020
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2023 - 01/2019
2	Multiple Sclerosis 01/2023 - 01/2019
2	Retinal Degeneration 07/2021 - 01/2018
2	Optic Nerve Diseases (Optic Neuropathy) 07/2018 - 01/2018
1	Inflammation (Inflammations) 01/2023
1	Pain (Aches) 01/2023
1	Edema (Dropsy) 01/2023
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023
1	Vision Disorders (Hemeralopia) 05/2022
1	Uveitis 05/2022
1	Blindness (Hysterical Blindness) 05/2022
1	Macular Degeneration (Age-Related Maculopathy) 05/2022
1	Diabetic Retinopathy (Retinopathy, Diabetic) 05/2022
1	Eye Diseases (Eye Disease) 05/2022
1	Choroidal Neovascularization 05/2022
1	Neuroblastoma 07/2021
1	Hyperalgesia 01/2019
1	Disease Progression 01/2019
1	Endometriosis 01/2019
1	Ischemia 01/2018
1	Hearing Loss (Hearing Impairment) 05/2016
1	Brain Edema (Cerebral Edema) 05/2016
1	Macular Edema 05/2016
1	Heart Failure 05/2016
1	Vertigo (Positional Vertigo) 05/2016
1	Pulmonary Edema 05/2016
1	Cataract (Cataracts) 04/2010
1	B-Cell Lymphoma (Lymphoma, B Cell) 03/2010
1	Wounds and Injuries (Trauma) 03/2010
1	Gliosis 03/2010
1	Miosis 10/2006
1	Ocular Hypotension 10/2006

Drug/Important Bio-Agent (IBA)

4	Retinaldehyde (Retinal)IBA 01/2023 - 03/2010
3	EstersIBA 04/2010 - 09/2004
2	ProstaglandinsIBA 01/2023 - 01/2019
2	AL 8810IBA 12/2020 - 01/2019
2	Travoprost (Travatan)FDA Link 12/2020 - 04/2010
2	prostaglandin F2alpha receptorIBA 01/2019 - 10/2006
2	AcidsIBA 01/2018 - 04/2010
2	1-(2-aminopropyl)-1H-indazole-6-olIBA 08/2010 - 02/2007
2	ProdrugsIBA 10/2006 - 09/2004
2	AL-12182IBA 10/2006 - 09/2004
1	Environmental Pollutants (Pollutants, Environmental)IBA 05/2022
1	platelet activating factor receptorIBA 05/2022
1	UbiquitinIBA 07/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2021
1	Lithium ChlorideIBA 07/2021
1	Rilmenidine (Hyperium)IBA 07/2021
1	TOR Serine-Threonine KinasesIBA 07/2021
1	Proteasome InhibitorsIBA 07/2021
1	emedastine FDA Link 12/2020
1	Olopatadine Hydrochloride (Patanol)FDA Link 12/2020
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2019
1	CalciumIBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Kainic Acid (Kainate)IBA 01/2018
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018
1	N-Methylaspartate (NMDA)IBA 01/2018
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2018
1	Glutamic Acid (Glutamate)FDA Link 01/2018
1	Excitatory Amino AcidsIBA 01/2018
1	Aquaporins (Water Channels)IBA 05/2016
1	ReninIBA 04/2015
1	KininsIBA 04/2015
1	Kallikreins (Kallikrein)IBA 04/2015
1	AngiotensinsIBA 04/2015
1	BradykininIBA 04/2015
1	trichostatin A (A 300)IBA 08/2010
1	Bimatoprost (Lumigan)FDA Link 04/2010
1	AmidesIBA 04/2010
1	Ophthalmic Solutions (Eye Drops)IBA 04/2010
1	Glial Fibrillary Acidic ProteinIBA 03/2010
1	bcl-X ProteinIBA 03/2010
1	Prostaglandins FIBA 01/2009
1	Latanoprost (Xalatan)FDA Link 01/2009
1	Synthetic Prostaglandins (Prostaglandin Analogues)IBA 01/2009
1	Serotonin (5 Hydroxytryptamine)IBA 01/2006
1	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 07/2003

Therapy/Procedure

3	Therapeutics 01/2021 - 07/2018
2	Lasers (Laser) 10/2006 - 07/2003
1	Intravitreal Injections 07/2021